Episode: S3.18 Exposed
Scene: Sylar is holding Luke to the Wall and beginning to cut his head open.

Luke (screaming): “Why are you doing this to me?”
Sylar: “Because you’re here and I need to express my feelings. You used me for some joyride and escape. I’ve got news for you, kid: There is no escape. There’s only pain. And you can never outrun it; no matter what you do, no matter where you go.”